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免疫抑制治疗和血浆置换三年后循环抗肾小球基底膜抗体复发。

Recurrence of circulating anti-glomerular basement membrane antibody three years after immunosuppressive treatment and plasma exchange.

作者信息

Hind C R, Bowman C, Winearls C G, Lockwood C M

出版信息

Clin Nephrol. 1984 Apr;21(4):244-6.

PMID:6733989
Abstract

A patient with auto-antibody mediated Goodpasture's syndrome was successfully treated with cytotoxic drugs, steroids and plasma exchange. After an absence of three years, circulating anti-glomerular basement membrane antibodies reappeared, and linear IgG staining of the glomeruli was shown by immunofluorescent studies. Renal function did not change and there was no evidence of pulmonary hemorrhage. Antibody levels then fell spontaneously over the succeeding 18 months.

摘要

一名自身抗体介导的肺出血肾炎综合征患者通过细胞毒性药物、类固醇和血浆置换成功治愈。三年后,循环抗肾小球基底膜抗体再次出现,免疫荧光研究显示肾小球有线性IgG染色。肾功能未改变,也没有肺出血的迹象。随后抗体水平在接下来的18个月内自发下降。

相似文献

1
Recurrence of circulating anti-glomerular basement membrane antibody three years after immunosuppressive treatment and plasma exchange.免疫抑制治疗和血浆置换三年后循环抗肾小球基底膜抗体复发。
Clin Nephrol. 1984 Apr;21(4):244-6.
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Failure of plasma exchange and immunosuppression to improve renal function in Goodpasture's syndrome.血浆置换和免疫抑制未能改善肺出血肾炎综合征的肾功能。
Clin Nephrol. 1978 Aug;10(2):71-3.
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Transplantation, immunosuppression and plasmapheresis in Goodpasture's syndrome.肺出血肾炎综合征中的移植、免疫抑制及血浆置换
Clin Nephrol. 1978 Mar;9(3):126-8.
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Immunoadsorption in Goodpasture's syndrome.肺出血肾炎综合征中的免疫吸附疗法。
Am J Kidney Dis. 2000 Aug;36(2):392-5. doi: 10.1053/ajkd.2000.8993.
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Goodpasture's syndrome with asymptomatic renal involvement. Disappearance of antiglomerular basement membrane antibodies deposits after treatment.伴有无症状性肾脏受累的Goodpasture综合征。治疗后抗肾小球基底膜抗体沉积物消失。
Nephrol Dial Transplant. 1993;8(11):1267-9.
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Goodpasture's disease in the absence of circulating anti-glomerular basement membrane antibodies as detected by standard techniques.经标准技术检测,无循环抗肾小球基底膜抗体情况下的肺出血肾炎综合征。
Am J Kidney Dis. 2002 Jun;39(6):1162-7. doi: 10.1053/ajkd.2002.33385.
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Goodpasture's syndrome--local and diffuse deposition of antibody in glomerular basement membrane. Case report.肺出血肾炎综合征——抗体在肾小球基底膜的局部及弥漫性沉积。病例报告。
Clin Nephrol. 1983 Jul;20(1):44-8.
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Pulmonary hemorrhage in Goodpasture's syndrome.肺出血-肾炎综合征中的肺出血
N Engl J Med. 1976 Dec 16;295(25):1430-2. doi: 10.1056/NEJM197612162952509.
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Anti-basement membrane antibodies in immunologic renal disease.免疫性肾脏疾病中的抗基底膜抗体。
Aust N Z J Med. 1981;11(Suppl 1):94-100.
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The spectrum of renal diseases associated with anti-basement membrane antibodies.与抗基底膜抗体相关的肾脏疾病谱。
Arch Intern Med. 1980 Jan;140(1):79-81.

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