[Pre- and postoperative fibronectin concentrations in the serum of patients with severe peritonitis in comparison with postoperative courses without complications].

Fibronectin in serum was determined in surgical patients with and without severe peritonitis. It could be observed that the infection induced an intense reduction of fibronectin, which could not be found in patients without postoperative complications. Extremely low values were detected in patients not surviving the infection. They remain unchanged during the observation time. Patients with severe infections, which survived, did show higher fibronectin values which significantly increased during the observation time. Together with other parameters and clinical symptoms fibronectin could be used to indicate the prognosis of severe infections.