Fisher R J
Equine Vet J. 1984 May;16(3):176-9. doi: 10.1111/j.2042-3306.1984.tb01895.x.
Ketamine was used on 80 occasions to induce anaesthesia in 77 animals. Xylazine premedication was used alone on 75 occasions, in conjunction with methadone once, in conjunction with methadone and acepromazine once and, on three occasions, methadone and acepromazine only were used. Anaesthesia was maintained in seven cases with halothane and oxygen. Premedication with xylazine 5 mins previously or concurrently with ketamine gave similar results but an interval of more than 5 mins between the drugs produced less deep anaesthesia and this protocol is, therefore, not advised. Induction and recovery were judged to be good in 82 per cent and 78 per cent of cases, respectively, and analgesia and muscle relaxation were judged as adequate in 79 per cent of cases.
氯胺酮在80次麻醉诱导中用于77只动物。单独使用甲苯噻嗪进行术前用药75次,与美沙酮联合使用1次,与美沙酮和乙酰丙嗪联合使用1次,另有3次仅使用美沙酮和乙酰丙嗪。7例使用氟烷和氧气维持麻醉。术前5分钟或与氯胺酮同时使用甲苯噻嗪产生的效果相似,但两种药物之间间隔超过5分钟会导致麻醉深度降低,因此不建议采用此方案。分别有82%和78%的病例诱导期和恢复期情况良好,79%的病例镇痛和肌肉松弛效果充分。