Burghardt E, Pickel H, Stettner H
Eur J Gynaecol Oncol. 1984;5(3):155-9.
Since the end of 1979 extensive pelvic lymphadenectomy has been performed at the Graz University Clinic of Obstetrics and Gynecology in the operative treatment of ovarian cancer in stages Ib to IV. In 27 of 48 patients (56.3%) positive nodes were found. The frequency of involved nodes in stage III only was 61.1% (N = 22). The incidence of positive paraaortic nodes in 16 evaluated cases was 31.2%, but these were only found when pelvic nodes were involved too. In 12 cases lymphadenectomy was done in second-look laparotomy. It became apparent that after operative and cytotoxic treatment with Adriamycin, Cis-Platinum and Cyclophosphamide (following the regimen of Ehrlich et al.) pelvic lymphnodes were still found positive in 8 of 12 cases (66.7%). The distribution of the nodes involved showed that the caudal lymphnodes were more often affected that than cranial ones. The results so far suggest that extensive pelvic lymphadenectomy may improve survival rates of patients with advanced ovarian cancer.
自1979年底以来，格拉茨大学妇产科诊所对Ib至IV期卵巢癌患者进行手术治疗时均实施了广泛盆腔淋巴结清扫术。48例患者中有27例（56.3%）发现有阳性淋巴结。仅III期患者的淋巴结受累频率为61.1%（N = 22）。在16例接受评估的病例中，腹主动脉旁淋巴结阳性的发生率为31.2%，但这些情况仅在盆腔淋巴结也受累时才被发现。12例患者在二次剖腹探查术中进行了淋巴结清扫术。结果显示，在用阿霉素、顺铂和环磷酰胺进行手术及细胞毒性治疗后（按照埃利希等人的方案），12例患者中有8例（66.7%）盆腔淋巴结仍为阳性。受累淋巴结的分布情况表明，尾侧淋巴结比头侧淋巴结更常受累。目前的结果表明，广泛盆腔淋巴结清扫术可能会提高晚期卵巢癌患者的生存率。
