Burghardt E, Pickel H, Lahousen M, Stettner H
Am J Obstet Gynecol. 1986 Aug;155(2):315-9. doi: 10.1016/0002-9378(86)90817-3.
From the end of 1979 to September, 1985, radical pelvic lymphadenectomy was performed at the Graz Clinic in 123 cases of Stages IA to IV ovarian cancer following maximum debulking procedure. In 97 patients lymphadenectomy was done primarily. In 26 it was performed during a follow-up operation to chemotherapy. The frequency of pelvic node involvement was 61.8% in the total material and 78.0% in 82 cases of Stage III disease only; 75.0% positive nodes were found in Stage III after chemotherapy. Aortic nodes were positive in 41.4%, but only when pelvic nodes were also positive. The 5-year actuarial survival rate for Stage III disease was 53.0% after pelvic lymphadenectomy compared with 13.0% without. In cases with negative nodes the survival rate was 74.7%; with positive nodes the survival rate was 45.9%.
1979年底至1985年9月,格拉茨诊所对123例IA至IV期卵巢癌患者在进行最大程度肿瘤减灭术后施行盆腔根治性淋巴结切除术。97例患者首先进行了淋巴结切除术。26例是在化疗后的随访手术中进行的。盆腔淋巴结受累的发生率在全部病例中为61.8%,仅在82例III期疾病中为78.0%;化疗后III期患者中75.0%的淋巴结呈阳性。主动脉旁淋巴结阳性率为41.4%,但仅在盆腔淋巴结也为阳性时出现。III期疾病患者盆腔淋巴结切除术后的5年精算生存率为53.0%,未进行盆腔淋巴结切除术的患者为13.0%。淋巴结阴性的患者生存率为74.7%;淋巴结阳性的患者生存率为45.9%。