Brown C H
Exp Aging Res. 1984 Spring;10(1):35-8. doi: 10.1080/03610738408258539.
The loss of the ability to localize sounds was discovered to occur in rats as a consequence of aging. Subjects were trained in a two-alternative forced-choice paradigm to press the left bar if a sound was presented from the left side and to press the right bar if sound was presented from the right side. Testing was conducted with a brief 200 msec pink noise signal. The accuracy of sound localization was measured in rats from 10 to 21 months of age. By 21 months of age the accuracy of localization had declined from greater than 90% correct to less than 69% correct. The loss of the ability to localize sounds may be involved with the onset of spatial disorientation observed in some subjects at advanced ages.
研究发现，随着年龄增长，大鼠会出现声音定位能力丧失的情况。实验对象在二选一强制选择范式中接受训练，若声音从左侧发出则按压左侧杠杆，若声音从右侧发出则按压右侧杠杆。测试采用持续200毫秒的简短粉红噪声信号。对10至21月龄的大鼠进行声音定位准确性测量。到21月龄时，定位准确性已从高于90%的正确率降至低于69%的正确率。声音定位能力的丧失可能与一些高龄受试者出现的空间定向障碍有关。
