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[皮质和下丘脑神经元对反复窒息的耐受性]

[Resistance of cortical and hypothalamic neurons to recurrent asphyxia].

作者信息

Kuz'mina T R, Ianvareva I N, Verbianova O M

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1984 Apr;70(4):411-8.

PMID:6734834
Abstract

Asphyxia produced by discontinuing of artificial respiration for 3-5 min in curarized cats, was well tolerated by some neurons of the cerebral and hypothalamus cortex even when repeated a few times with the interval between asphyxias from 40 to 60 min. In most cases neurons even increased their resistance against subsequent effect of acute oxygen insufficiency preserving for a longer time the spontaneous impulse activity during the second and the third asphyxia.

摘要

在箭毒化的猫身上,通过停止人工呼吸3至5分钟产生的窒息状态,大脑和下丘脑皮质的一些神经元能够很好地耐受,即使窒息以40至60分钟的间隔重复几次也是如此。在大多数情况下,神经元甚至增强了它们对随后急性缺氧影响的抵抗力,在第二次和第三次窒息期间能更长时间地保持自发冲动活动。

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