Lantta M, Kahanpää K, Kärkkäinen J, Lehtovirta P, Wahlström T, Widholm O
Gynecol Oncol. 1984 Jun;18(2):233-9. doi: 10.1016/0090-8258(84)90031-3.
The presence of estradiol and progesterone receptors in endometrial stromal sarcoma (ESS) has not been studied previously. Two cases of ESS are reported in which high concentrations of these receptors were found in the tumor tissue. One of these patients had retained the reactivity to hormone treatment for several years. It is suggested that the steroid receptors should be analyzed in all cases of ESS to find tumors with a high receptor content. Hormone treatment of these patients should be part of the primary adjuvant therapy. In cases of a good response the therapy should be prolonged and continued for the rest of the patient's life.
此前尚未对子宫内膜间质肉瘤（ESS）中雌二醇和孕酮受体的存在情况进行研究。本文报告了两例ESS病例，其肿瘤组织中发现了高浓度的这些受体。其中一名患者对激素治疗的反应持续了数年。建议对所有ESS病例进行类固醇受体分析，以找出受体含量高的肿瘤。这些患者的激素治疗应作为主要辅助治疗的一部分。如果反应良好，治疗应延长并持续患者余生。
