Fritz K W, Lüllwitz E, Kirchner E
Fortschr Neurol Psychiatr. 1984 May;52(5):147-51. doi: 10.1055/s-2007-1002012.
Haemodynamic effects in 10 multi-injured patients were registered after a bolus injection of 20 mg fluphenazin-dihydrochloride (Dapotum acutum; Fa. Heyden). Favourable results were seen in pre- and afterload. Parameters such as TTI, TTIB, CE and TI, characterising myocardial oxygen consumption, were also influenced positively. A reduction of mean arterial pressure can be avoided by administering slowly increasing volume and, occasionally, catecholamines. By use of modern monitoring in ICV, thus drug seems to be free from risk.
对10例多发伤患者静脉推注20毫克盐酸氟奋乃静（Dapotum acutum；Heyden公司生产）后记录血流动力学效应。在前负荷和后负荷方面均观察到良好效果。表征心肌耗氧量的参数如TTI、TTIB、CE和TI也受到积极影响。通过缓慢增加液体量并偶尔使用儿茶酚胺，可以避免平均动脉压降低。通过在重症监护病房使用现代监测手段，这种药物似乎没有风险。
