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庆大霉素-甲硝唑在阑尾切除术和结直肠手术中的全身预防性应用:一项前瞻性对照临床研究。

Systemic prophylaxis with gentamicin-metronidazole in appendicectomy and colorectal surgery: a prospective controlled clinical study.

作者信息

Gómez-Alonso A, Lozano F, Pérez A, Almazán A, Abdel-lah A, Cuadrado F

出版信息

Int Surg. 1984 Jan-Mar;69(1):17-20.

PMID:6735625
Abstract

A prospective, randomized, clinical study was carried out in 188 patients undergoing appendicectomy or colorectal surgery to test the efficacy of prophylactic, parenterally-administered antibiotics in the prevention of infection. The results show the effectiveness of the association gentamicin-metronidazole (9.4% of infections), compared to the control group with no antibiotics (39.1% of infections), X2 = 14.1; P less than 0.001).

摘要

对188例接受阑尾切除术或结直肠手术的患者进行了一项前瞻性随机临床研究,以测试预防性胃肠外使用抗生素预防感染的疗效。结果显示庆大霉素-甲硝唑联合使用的有效性(感染率为9.4%),与未使用抗生素的对照组相比(感染率为39.1%),X2 = 14.1;P<0.001)。

相似文献

1
Systemic prophylaxis with gentamicin-metronidazole in appendicectomy and colorectal surgery: a prospective controlled clinical study.庆大霉素-甲硝唑在阑尾切除术和结直肠手术中的全身预防性应用:一项前瞻性对照临床研究。
Int Surg. 1984 Jan-Mar;69(1):17-20.
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[A randomized prospective study of antibiotic prophylaxis compared to lavage of the surgical wound in nonperforating appendicitis].非穿孔性阑尾炎中抗生素预防与手术伤口灌洗的随机前瞻性研究
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BMC Infect Dis. 2006 Jul 12;6:111. doi: 10.1186/1471-2334-6-111.
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A comparison of three different prophylactic parenteral antibiotic regimens in colorectal surgery: a prospective study.结直肠手术中三种不同预防性肠外抗生素方案的比较:一项前瞻性研究。
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Comparison of systemic prophylaxis with metronidazole/placebo and metronidazole/fosfomycin in colorectal surgery. A clinical study demonstrating the need for additional anti-aerobic prophylactic cover.甲硝唑/安慰剂与甲硝唑/磷霉素用于结直肠手术全身预防的比较。一项临床研究表明需要额外的抗需氧菌预防性覆盖。
Acta Chir Scand. 1984;150(4):317-23.
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Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin.儿童急性非穿孔性阑尾炎的抗生素预防:单剂量甲硝唑和庆大霉素。
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[Perioperative antibiotic prevention in colon and rectum surgery. A randomized study on the value of single dose prevention].[结肠和直肠手术围手术期抗生素预防。单剂量预防价值的随机研究]
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Wound sepsis after colorectal surgery: the effect of cefotetan lavage.结直肠手术后的伤口感染:头孢替坦灌洗的效果
Chemioterapia. 1987 Jun;6(2 Suppl):595-6.

引用本文的文献

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Antimicrobial prophylaxis in colorectal surgery: focus on ertapenem.结直肠手术中的抗菌预防:重点关注厄他培南。
Ther Clin Risk Manag. 2009;5:829-39. doi: 10.2147/tcrm.s3101. Epub 2009 Nov 2.
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Antibiotics versus placebo for prevention of postoperative infection after appendicectomy.抗生素与安慰剂预防阑尾切除术后感染的比较
Cochrane Database Syst Rev. 2005 Jul 20;2005(3):CD001439. doi: 10.1002/14651858.CD001439.pub2.
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Antimicrobial prophylaxis in colorectal surgery.结直肠手术中的抗菌药物预防
Qual Health Care. 1999 Jun;8(2):132-6. doi: 10.1136/qshc.8.2.132.