Gómez-Alonso A, Lozano F, Pérez A, Almazán A, Abdel-lah A, Cuadrado F
Int Surg. 1984 Jan-Mar;69(1):17-20.
A prospective, randomized, clinical study was carried out in 188 patients undergoing appendicectomy or colorectal surgery to test the efficacy of prophylactic, parenterally-administered antibiotics in the prevention of infection. The results show the effectiveness of the association gentamicin-metronidazole (9.4% of infections), compared to the control group with no antibiotics (39.1% of infections), X2 = 14.1; P less than 0.001).
对188例接受阑尾切除术或结直肠手术的患者进行了一项前瞻性随机临床研究,以测试预防性胃肠外使用抗生素预防感染的疗效。结果显示庆大霉素-甲硝唑联合使用的有效性(感染率为9.4%),与未使用抗生素的对照组相比(感染率为39.1%),X2 = 14.1;P<0.001)。