Ryhänen P, Hanhela R, Jouppila R, Vuopala U
Int Surg. 1984 Jan-Mar;69(1):29-33.
The cardiovascular changes in 27 hypertensive patients belonging to WHO classes I-II and treated with either clonidine, methyldopa or reserpine during thiopentone-N2O-O2-relaxant-analgesic anesthesia were studied. The variations in systolic and diastolic blood pressure and heart rate during induction of anesthesia and surgery did not differ according to the antihypertensive drug with which the patient was treated. Hypokalemia was found to be the most common postoperative complication in all study groups. The results suggest that the selection of antihypertensive drug does not form a risk factor when hypertensive patients are being prepared for anesthesia and surgery.
对27例世界卫生组织I-II级高血压患者在硫喷妥钠-氧化亚氮-氧气-肌松剂-镇痛麻醉期间使用可乐定、甲基多巴或利血平治疗时的心血管变化进行了研究。麻醉诱导和手术期间收缩压、舒张压和心率的变化与患者所使用的抗高血压药物无关。低钾血症是所有研究组中最常见的术后并发症。结果表明,在为高血压患者准备麻醉和手术时,抗高血压药物的选择并非危险因素。