Geggel H S, Friend J, Thoft R A
Invest Ophthalmol Vis Sci. 1984 Jul;25(7):860-3.
In vivo conjunctival epithelial healing in albino rabbits was investigated by light microscopy following both n-heptanol and trephined conjunctival wounding. Reepithelialization occurred faster following n-heptanol treatment (3 days) versus trephination (6-7 days). No goblet cells were present in the migrating epithelium during reepithelialization. After 1 day of wounding, goblet cells disappeared several millimeters peripheral to the wound margin in both types of wounds. Goblet cells first reappeared peripherally 1 week after wounding before they appeared in the central wound area. These observations indicate that a large area of conjunctival epithelium surrounding a wound is involved with repair of that wound. Since the goblet cell content of conjunctival epithelium appears to change as a result of the stresses of epithelial repair, the goblet cell population may reflect the presence of reparative or proliferative processes in the ocular surface.
通过光学显微镜研究了白化兔在正庚醇和环钻结膜损伤后体内结膜上皮的愈合情况。与环钻术（6 - 7天）相比，正庚醇处理后（3天）上皮再形成发生得更快。在上皮再形成过程中，迁移的上皮中没有杯状细胞。损伤1天后，两种类型的伤口在伤口边缘外周几毫米处杯状细胞消失。杯状细胞在伤口外周首先在受伤1周后重新出现，然后才出现在伤口中央区域。这些观察结果表明，伤口周围大面积的结膜上皮参与了该伤口的修复。由于结膜上皮的杯状细胞含量似乎因上皮修复的应激而发生变化，杯状细胞群体可能反映了眼表修复或增殖过程的存在。
