Woolf N K, Ryan A F
Hear Res. 1984 Mar;13(3):277-83. doi: 10.1016/0378-5955(84)90081-9.
Cochlear microphonic (CM) potentials were recorded throughout the development of auditory function in the Mongolian gerbil. CM responses were first recorded at 12 days after birth (DAB), with thresholds exceeding 103 dB SPL. CM thresholds subsequently improved rapidly in a parallel fashion across the responsive frequency range, achieving adult levels by 18 DAB. There was no evidence from CM thresholds of a preferential rate of maturation for either the high or low frequency ranges. CM responses to suptrathreshold stimulation were also studied throughout development. At all responsive ages, CM input-output functions increased logarithmically to a saturating maximum value and then declined. Maximum CM responses increased continuously throughout development in a parallel fashion across all frequencies. The dynamic range of the CM input-output functions (the intensity interval from CM threshold to maximum CM value) also developed in a parallel manner across frequencies, but reached mature assymptotic values by 16 DAB. The results suggest that throughout the adult CM frequency range cochlear hair cell function develops simultaneously.
在蒙古沙鼠听觉功能发育的整个过程中记录了耳蜗微音器（CM）电位。CM反应在出生后12天（DAB）首次记录到，阈值超过103 dB SPL。随后，CM阈值在整个反应频率范围内以平行方式迅速改善，到18 DAB时达到成年水平。从CM阈值没有证据表明高频或低频范围有优先成熟率。在整个发育过程中也研究了CM对阈上刺激的反应。在所有有反应的年龄，CM输入-输出函数对数增加至饱和最大值，然后下降。最大CM反应在整个发育过程中在所有频率上以平行方式持续增加。CM输入-输出函数的动态范围（从CM阈值到最大CM值的强度区间）在各频率上也以平行方式发展，但在16 DAB时达到成熟渐近值。结果表明，在整个成年CM频率范围内，耳蜗毛细胞功能同时发育。
