de Gennes J L, Turpin G, Heshmati H M, Cesselin E, Lagoguey M
Nouv Presse Med. 1978 May 20;7(20):1713-7.
Complete endocrinological studies were made before and after surgery in 18 cases of prolactin adenoma (2 giant adenomas and 16 macro-adenomas). Certain points are stressed: the frequency of the haemorrhagic nature of the adenoma in 4 cases, including 1 case of spontaneous necrosis; the great variability in dynamic responses to the TRH stimulation test or inhibition by I-Dopa; the persistence in 14 cases out of 16 of postoperative hyperproclactinaemia, requiring the prescription of 5 to 10 mg/day of bromocriptine, rarely more; the disappearance of total impotence in two male cases as a result of the latter drug, whilst testerone and dihydrotestosterone levels were normal before the beginning of medical treatment.
对18例催乳素腺瘤（2例巨大腺瘤和16例大腺瘤）患者在手术前后进行了全面的内分泌学研究。着重强调了以下几点：4例腺瘤具有出血性质，其中1例为自发性坏死；对促甲状腺激素释放激素（TRH）刺激试验或左旋多巴抑制的动态反应差异很大；16例中有14例术后高催乳素血症持续存在，需要服用5至10毫克/天的溴隐亭，很少超过此剂量；两名男性患者因服用该药完全阳痿消失，而在开始药物治疗前睾酮和双氢睾酮水平正常。
