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不育症治疗后妊娠期间泌乳素分泌性腺瘤急性加重。2例(作者译)

[Acute exacerbation of prolactin-secreting adenomas during pregnancy following the treatment of sterility. 2 cases (author's transl)].

作者信息

Le Pogamp C, Grall J Y, Massart C, Ramée A, Toulouse R

出版信息

Nouv Presse Med. 1979 Jun 2;8(24):2009-11.

PMID:492990
Abstract

These 2 cases were similar in terms of the time of onset of problems at the 8th month, the clinical and radiological signs of the tumour, and the existence of an amenorrhoea-galactorrhoea syndrome with hyperprolactinaemia. They differed with regard to the mode in which the pregnancy was obtained: one was induced by anti-prolactins in the presence of a normal sella turcica whilst the other began during the cycle following the administration of clomiphene with no prior radiological study of the sella turcica. They also differed in terms of the course: intra-tumoural haematoma requiring early surgery in one, hyperplasia and oedema regressing after delivery in the other making it possible to avoid immediate treatment.

摘要

这2例在问题出现时间(均为第8个月)、肿瘤的临床和放射学体征以及存在伴有高泌乳素血症的闭经-溢乳综合征方面相似。它们在受孕方式上有所不同:一例是在蝶鞍正常的情况下由抗催乳素诱导受孕,而另一例是在服用克罗米芬后的周期内受孕,之前未对蝶鞍进行放射学检查。它们在病程方面也存在差异:一例出现肿瘤内血肿需要早期手术,另一例在产后增生和水肿消退,从而避免了立即治疗。

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