Kraus S E, Siroky M B, Babayan R K, Krane R J
J Urol. 1984 Aug;132(2):288-90. doi: 10.1016/s0022-5347(17)49599-1.
We reviewed 116 consecutive adults hospitalized for hematuria (92 with gross and 24 with microscopic hematuria). The cause of hematuria (that is neoplasia, stones, infection and inflammation) was recognized in approximately 79 per cent of the 116 patients (group 1), while 21 per cent (group 2) had idiopathic hematuria. Review of drug history in these 2 groups revealed that nonsteroidal anti-inflammatory drugs were used in 1 per cent of the patients in group 1 compared to 54 per cent in group 2. To confirm these findings we reviewed a control group of 60 patients without hematuria hospitalized for benign prostatic hyperplasia and followup of bladder tumors, and found a 3.3 per cent prevalence of nonsteroidal anti-inflammatory drugs. These findings implicate nonsteroidal anti-inflammatory drug use as a potential cause of idiopathic hematuria.
我们回顾性分析了116例因血尿住院的成年患者（92例为肉眼血尿，24例为镜下血尿）。在这116例患者中，约79%（第1组）的血尿病因（即肿瘤、结石、感染和炎症）得以明确，而21%（第2组）为特发性血尿。对这两组患者的用药史进行回顾发现，第1组中1%的患者使用过非甾体抗炎药，而第2组中这一比例为54%。为证实这些发现，我们回顾性分析了一组60例因良性前列腺增生和膀胱肿瘤随访而住院但无血尿的对照患者，发现非甾体抗炎药的使用率为3.3%。这些发现提示使用非甾体抗炎药可能是特发性血尿的一个潜在病因。
