Tremper K K, Konchigeri H N, Cullen B F, Kapur P A, Thangathurai D, Percival C
J Thorac Cardiovasc Surg. 1984 Jul;88(1):22-5.
Twenty adult patients were monitored with a transcutaneous oxygen tension sensor during one-lung ventilation. Anesthesia was maintained with enflurane-oxygen or isoflurane-oxygen. The transcutaneous oxygen tension values accurately followed the trend of arterial oxygen tension (r = 0.94, n = 96, transcutaneous oxygen tension = 4.8 + 0.78 X arterial oxygen tension). The transcutaneous oxygen tension values averaged 80% of the arterial oxygen tension values (transcutaneous oxygen tension index = transcutaneous oxygen tension/arterial oxygen tension = 0.80 +/- 0.18) (mean +/- standard deviation). When one-lung ventilation was initiated, there was a progressive drop in transcutaneous oxygen tension which reached a minimum of 19 +/- 10 minutes. The mean of the minimum transcutaneous oxygen tension and arterial oxygen tension values was 66 +/- 44 torr and 83 +/- 43 respectively. This resulted in a mean alveolar-arterial oxygen gradient of 515 +/- 152 torr during one-lung ventilation. In eight patients, the arterial oxygen tension fell below 60 torr, 45 +/- 9 torr. When two-lung ventilation was resumed, the transcutaneous oxygen tension and arterial oxygen tension values promptly rose to mean values of 342 +/- 121 torr and 411 +/- 103 torr, respectively in 9 +/- 3 minutes. The transcutaneous oxygen tension monitor provided a continuous assessment of the patient's oxygenation, gave early warning of potentially hazardous hypoxia, and permitted nearly real-time assessment of the efficacy of corrective therapies.
在单肺通气期间，使用经皮氧分压传感器对20名成年患者进行监测。采用恩氟烷-氧气或异氟烷-氧气维持麻醉。经皮氧分压值准确地跟随动脉血氧分压的变化趋势（r = 0.94，n = 96，经皮氧分压 = 4.8 + 0.78×动脉血氧分压）。经皮氧分压值平均为动脉血氧分压值的80%（经皮氧分压指数 = 经皮氧分压/动脉血氧分压 = 0.80±0.18）（均值±标准差）。当开始单肺通气时，经皮氧分压逐渐下降，在19±10分钟时达到最低值。最低经皮氧分压值和动脉血氧分压值的均值分别为66±44托和83±43托。这导致单肺通气期间平均肺泡-动脉氧分压差为515±152托。在8名患者中，动脉血氧分压降至60托以下，为45±9托。当恢复双肺通气时，经皮氧分压值和动脉血氧分压值在9±3分钟内迅速分别升至均值342±121托和411±103托。经皮氧分压监测仪能够持续评估患者的氧合情况，对潜在的危险低氧血症发出早期预警，并允许对纠正治疗的效果进行近乎实时的评估。
