Viitanen A, Salmenperä M, Heinonen J
J Clin Monit. 1987 Apr;3(2):90-5. doi: 10.1007/BF00858356.
Oxygenation was monitored concomitantly by measurement of transcutaneous oxygen tension and by pulse oximetry, and the data were compared with arterial blood oxygen tension and saturation values in 10 patients who became hypoxemic when undergoing thoracotomy and one-lung ventilation. A steep decrease in arterial blood oxygen tension was obvious immediately after the institution of one-lung ventilation, reaching the lowest mean value of 63 +/- 2 mm Hg (+/- SEM) at 12 minutes. Despite significant correlation between transcutaneous oxygen tension and arterial blood oxygen tension during one-lung ventilation (r = 0.75; P less than 0.001), the delay in the transcutaneous oxygen tension response resulted in underestimation of the severity of hypoxemia at the beginning of one-lung ventilation. In contrast, the decrease in arterial blood oxygen saturation from 97.9 +/- 0.3% to 92.2 +/- 0.8% as measured by CO-Oximeter was accurately followed by pulse oximetry with almost beat-to-beat response, bringing about a highly significant linear correlation between the two methods (r = 0.93; P less than 0.001). We conclude that pulse oximetry is a simpler and more rapidly responding method than measurement of transcutaneous oxygen tension for detection of hypoxemia during one-lung ventilation in adults.
通过测量经皮氧分压和脉搏血氧饱和度来同步监测氧合情况，并将这些数据与10例开胸手术及单肺通气时出现低氧血症患者的动脉血氧分压和饱和度值进行比较。单肺通气开始后，动脉血氧分压立即明显急剧下降，在12分钟时达到最低平均值63±2 mmHg（±标准误）。尽管在单肺通气期间经皮氧分压与动脉血氧分压之间存在显著相关性（r = 0.75；P＜0.001），但经皮氧分压反应的延迟导致在单肺通气开始时低估了低氧血症的严重程度。相比之下，用CO - 血氧计测得的动脉血氧饱和度从97.9±0.3%降至92.2±0.8%，脉搏血氧饱和度几乎逐搏准确跟踪，两种方法之间呈现高度显著的线性相关性（r = 0.93；P＜0.001）。我们得出结论，对于检测成人单肺通气期间的低氧血症，脉搏血氧饱和度测定法比测量经皮氧分压更简单且反应更快。
