Bittner R, Butters M, Schirrow H, Krautzberger W, Beger H G
Langenbecks Arch Chir. 1984;362(2):77-87. doi: 10.1007/BF01254182.
Between 1969 and 1983 a total of 152 patients underwent total gastrectomy. 58 patients were older than 70 years. Surgical lethality was 14.47% with only minor differences between those patients younger than 70 and the older ones: 13.8 and 15.5%, respectively. Moreover, it did not make any major difference whether surgery was curative or merely palliative. Of 27 patients with the tumor stage TNM IV, only one patient died. Of the 66, who were operated upon during the recent 5 years period between 1979 and 1983, only one patient died. These results suggest that this remarkable decline of lethality is due to a precise standardisation of surgical technique, improvements in preoperative management of the patient and aftercare. 5 years survival rate was 17.3%; again there was no major difference between the group of patients older than 70 and those being younger than 70 years (16.5% and 19.4% respectively). It is of interest that the patients having additional splenectomy presented with an essentially worse prognosis as opposed to those without splenectomy although there were no differences between the TNM-stages. Even if the small numbers of patients can not yet be definitely conclusive, these preliminary results indicate that the indication for splenectomy in the course of total gastrectomy should be critically evaluated.
1969年至1983年间,共有152例患者接受了全胃切除术。其中58例患者年龄超过70岁。手术死亡率为14.47%,70岁以下患者和70岁以上患者之间仅有微小差异,分别为13.8%和15.5%。此外,手术是根治性的还是仅仅是姑息性的并没有太大区别。在27例肿瘤分期为TNM IV期的患者中,只有1例死亡。在1979年至1983年最近5年期间接受手术的66例患者中,只有1例死亡。这些结果表明,死亡率的显著下降归因于手术技术的精确标准化、患者术前管理和术后护理的改善。5年生存率为17.3%;70岁以上患者组和70岁以下患者组之间同样没有太大差异(分别为16.5%和19.4%)。有趣的是,与未进行脾切除术的患者相比,进行了额外脾切除术的患者预后明显更差,尽管TNM分期之间没有差异。即使患者数量较少尚不能得出明确结论,但这些初步结果表明,在全胃切除术中脾切除术的指征应进行严格评估。