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70岁以上胃癌患者的手术治疗(作者译)

[Surgery of gastric cancer in patients older than 70 years (author's transl)].

作者信息

Bittner R, Beger H G, Kraas E, Gögler H

出版信息

Langenbecks Arch Chir. 1978 Apr 7;344(4):293-307. doi: 10.1007/BF01261267.

DOI:10.1007/BF01261267
PMID:642653
Abstract

In this study it is reported about operative mortality and long-term results of surgery of gastric carcinoma in patients over the age of 70 years. The operative mortality in 50 patients with a distal partial gastrectomy was 16%, the mortality in 24 patients with total gastrectomy was 33.3% and in 14 patients with a proximal gastrectomy the mortality was 28%. The main cause of death (40%) was a pneumonia. There was no correlation between frequency of pneumonia and preoperative results of measurement of lung function. Only advanced arteriosclerotic disease in the heart and brain has a fatal influence on mortality rate. In the old patients the long-term results are determined by the staging of the tumor at the time of operation, too. In the 60 patients, who had left the hospital and who are in our control, the half year survival rate was 78.3%, the 1-year survival rate was 58.3% and the 2-years survival rate is exceeding 41.6%. 14 patients of the 17, who are still alive and who are after 2 1/2 years again explored, are in a very good condition. In comparison with the literature it is to conclude that for the indication to surgery of gastric carcinoma there is important not only the real age of the patient but rather the biological and mental condition of the patient.

摘要

本研究报告了70岁以上胃癌患者的手术死亡率及手术长期结果。50例行远端胃部分切除术患者的手术死亡率为16%,24例行全胃切除术患者的死亡率为33.3%,14例行近端胃切除术患者的死亡率为28%。主要死亡原因(40%)为肺炎。肺炎发生率与术前肺功能测量结果之间无相关性。仅心脏和脑部的晚期动脉硬化疾病对死亡率有致命影响。在老年患者中,长期结果也取决于手术时肿瘤的分期。在60例已出院并接受我们随访的患者中,半年生存率为78.3%,1年生存率为58.3%,2年生存率超过41.6%。在17例术后2年半仍存活且再次接受检查的患者中,14例状况良好。与文献相比,可以得出结论,对于胃癌手术适应证而言,重要的不仅是患者的实际年龄,更重要的是患者的生物学和精神状况。

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引用本文的文献

1
Gastric carcinoma: is radical gastrectomy worth while?胃癌:根治性胃切除术是否值得?
Ann R Coll Surg Engl. 1980 Jan;62(1):25-30.
2
[Gastrectomy in the aged].[老年患者的胃切除术]
Langenbecks Arch Chir. 1984;362(2):77-87. doi: 10.1007/BF01254182.

本文引用的文献

1
[SERUM PROTEINS AND PROGNOSIS IN CANCER AND SARCOMA OF THE STOMACH].
Langenbecks Arch Klin Chir Ver Dtsch Z Chir. 1964 Dec 21;307:355-66.
2
Major surgery in patients 70 years of age and over; an analysis of 146 operations on 135 patients.70岁及以上患者的大手术;对135例患者的146例手术进行分析。
Ann Surg. 1956 Jun;143(6):845-54. doi: 10.1097/00000658-195606000-00014.
3
[Old age surgical problems in stomach carcinoma. I. Old age surgery].老年胃癌的外科问题。一、老年外科手术
Z Alternsforsch. 1966 Sep;19(2):127-37.
4
Partial or total gastrectomy for adenocarcinoma of the cardia.贲门腺癌的部分或全胃切除术。
Acta Chir Scand. 1969;135(4):340-4.
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[The treatment of stomach cancer by total gastrectomy. Indications, technic and results].
Dtsch Med Wochenschr. 1968 Feb 23;93(8):329-35. doi: 10.1055/s-0028-1105063.
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[Experiences with stage classification of stomach cancer].[胃癌分期分类的经验]
Arch Geschwulstforsch. 1967;30(1):42-52.
7
Pathology and prognosis of carcinoma of the stomach.胃癌的病理学与预后
Br J Surg. 1970 Dec;57(12):877-83. doi: 10.1002/bjs.1800571202.
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[Results of total gastrectomy in stomach cancer].[胃癌全胃切除术的结果]
Langenbecks Arch Chir. 1969;325:450-8. doi: 10.1007/BF01255953.
9
[The lower partial resection of the stomach: Indications and results].[胃下部部分切除术:适应证与结果]
Langenbecks Arch Chir. 1969;325:439-50. doi: 10.1007/BF01255952.
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Total gastrectomy for gastric cancer. Clinical considerations on 431 cases.胃癌全胃切除术。431例临床考量
Cancer. 1972 Sep;30(3):660-4. doi: 10.1002/1097-0142(197209)30:3<660::aid-cncr2820300313>3.0.co;2-4.