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慢性镉中毒所致肝损伤

[Liver damage caused by chronic cadmium poisoning].

作者信息

Kaufmann I, Höpker W W, Deutsch-Diescher O G, Seitz H K, Götz R, Kommerell B

出版信息

Leber Magen Darm. 1984 May;14(3):103-6.

PMID:6738285
Abstract

A case report is given of a 46 year old person concerned professionally with melting gold, who exhibited bioptically and histologically verified lesions of the liver after chronic intoxication with cadmium. This patient was exposed throughout 8 years during his job activities to cadmium vapors. He exhibited during the time of investigation decreased renal function with tubular proteinuria as well as a polyneuropathy. In addition, hepatic lesions could be found, as small focal necrosis, fatty degeneration and fibrosis. Cadmium content of the liver was increased 13 times above normal.

摘要

本文报告了一例46岁职业从事黄金熔炼的患者,该患者在长期镉中毒后,经活检和组织学检查证实有肝脏病变。该患者在工作期间8年一直暴露于镉蒸气中。在调查期间,他出现肾功能下降伴肾小管蛋白尿以及多发性神经病变。此外,还发现了肝脏病变,如小灶性坏死、脂肪变性和纤维化。肝脏中的镉含量比正常水平高出13倍。

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