Turpin F, Lejeune F, Vilde J L, Le Coq D, Lotholary P, Paraf A
Nouv Rev Fr Hematol (1978). 1978 Apr 14;20(1):77-97.
A case associating a systemic mastocytosis and an acquired myeloperoxidase deficiency is reported. The myeloperoxydase deficiency is studied by cytochemical techniques in optical and electron microscopy and confirmed by biochemical measures. An important defect in bactericidal and candidacidal activity is demonstrated in vitro in P.N.M. The authors discuss the links between the two anomalies which might bring one more argument for the common origin of both granulocytes and mastocytes.
报告了一例系统性肥大细胞增多症与获得性髓过氧化物酶缺乏症相关联的病例。通过光学显微镜和电子显微镜下的细胞化学技术研究髓过氧化物酶缺乏情况,并通过生化检测加以证实。体外实验证明多形核中性粒细胞的杀菌和杀念珠菌活性存在重要缺陷。作者讨论了这两种异常之间的联系,这可能为粒细胞和肥大细胞的共同起源提供更多证据。