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与爱泼斯坦-巴尔病毒感染相关的暴发性肝衰竭和致命性脑病。

Fulminant hepatic failure and fatal encephalopathy associated with Epstein-Barr virus infection.

作者信息

Hart G K, Thompson W R, Schneider J, Davis N J, Oh T E

出版信息

Med J Aust. 1984 Jul 21;141(2):112-3. doi: 10.5694/j.1326-5377.1984.tb132717.x.

DOI:10.5694/j.1326-5377.1984.tb132717.x
PMID:6738423
Abstract

A case of fulminant hepatic failure, associated with infectious mononucleosis, in a previously healthy 14-year-old girl is reported. Despite intensive therapy, which included the use of acyclovir, charcoal haemoperfusion, and measures to control her raised intracranial pressure (guided by serial EEG and auditory brainstem-evoked response recordings), the outcome was fatal.

摘要

报告了一例14岁既往健康女孩发生的暴发性肝衰竭,该病例与传染性单核细胞增多症相关。尽管进行了强化治疗,包括使用阿昔洛韦、血液灌流活性炭,以及采取措施控制其升高的颅内压(通过连续脑电图和听觉脑干诱发电位记录进行指导),但结局仍为死亡。

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Fulminant hepatic failure and fatal encephalopathy associated with Epstein-Barr virus infection.与爱泼斯坦-巴尔病毒感染相关的暴发性肝衰竭和致命性脑病。
Med J Aust. 1984 Jul 21;141(2):112-3. doi: 10.5694/j.1326-5377.1984.tb132717.x.
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Epstein-Barr viral load assessment in immunocompetent patients with fulminant infectious mononucleosis.免疫功能正常的暴发性传染性单核细胞增多症患者的爱泼斯坦-巴尔病毒载量评估
Arch Intern Med. 2002 Apr 8;162(7):837-9. doi: 10.1001/archinte.162.7.837.
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Diagnosis of Hodgkin's disease hampered by an Epstein-Barr virus infection treated with acyclovir.由爱泼斯坦-巴尔病毒感染导致的霍奇金病诊断因使用阿昔洛韦治疗而受阻。
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[Neurologic complications of Epstein-Barr virus. Clinical contributions with a description of a complex case treated with acyclovir].
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Demonstration of Epstein-Barr virus DNA in a previously healthy boy with fulminant hepatic failure.在一名既往健康、患有暴发性肝衰竭的男孩中检测到爱泼斯坦-巴尔病毒DNA 。
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A case of fatal infectious mononucleosis presenting with fulminant hepatic failure associated with an extensive CD8-positive lymphocyte infiltration in the liver.一例致命性传染性单核细胞增多症,表现为暴发性肝衰竭,伴有肝脏广泛的CD8阳性淋巴细胞浸润。
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引用本文的文献

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A Rare Case of Epstein-Barr Virus Hepatitis and Rash in an Adolescent.一名青少年患爱泼斯坦-巴尔病毒肝炎并出疹的罕见病例。
Cureus. 2025 Jun 4;17(6):e85353. doi: 10.7759/cureus.85353. eCollection 2025 Jun.
2
Infectious mononucleosis hepatitis in young adults: two case reports.青年传染性单核细胞增多症性肝炎:两例报告。
Korean J Intern Med. 2009 Dec;24(4):381-7. doi: 10.3904/kjim.2009.24.4.381. Epub 2009 Nov 27.
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Demonstration of Epstein-Barr virus DNA in a previously healthy boy with fulminant hepatic failure.在一名既往健康、患有暴发性肝衰竭的男孩中检测到爱泼斯坦-巴尔病毒DNA 。
Eur J Pediatr. 1986 Apr;145(1-2):94-8. doi: 10.1007/BF00441865.