Chureeva L N, Budagov R S, Zaĭchik V E
Radiobiologiia. 1984 May-Jun;24(3):390-4.
A study was made of the dynamics of structural, morphological and histological changes in the thyroid gland of Wistar rats subjected to gamma-irradiation (7.5 Gy) and thermal burn (15% of a body surface) and a combined effect of these two factors. Concurrently, an estimation was made of the iodine content of the gland, using the roentgen-fluorescent method, and of the thyroxin concentration in blood. The results obtained were considered in relation to the clinical course and the outcome of the affection caused by the combined and individual effects of radiation and heat. It is conluded that the cell-tissue substrate providing the thyroid hormones synthesis does not undergo substantial variations from normal values which could be considered as a cause of the decrease in the hormone content of blood after burn, irradiation and the combined radiation and thermal injury. Other possible causes of hyperthyroxynemia are discussed.
对接受γ射线照射（7.5 Gy）和热烧伤（体表面积的15%）以及这两种因素联合作用的Wistar大鼠甲状腺的结构、形态和组织学变化动态进行了研究。同时，采用X射线荧光法对甲状腺的碘含量以及血液中的甲状腺素浓度进行了测定。将所得结果与辐射和热单独及联合作用所致疾病的临床病程和结局联系起来进行了分析。得出的结论是，提供甲状腺激素合成的细胞组织底物与正常值相比未发生实质性变化，而这可被视为烧伤、照射以及辐射与热联合损伤后血液中激素含量降低的原因。文中还讨论了甲状腺素血症的其他可能原因。
