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[大鼠子宫内发育期间甲状腺对单次γ射线照射的反应]

[Response of the developing thyroid gland of rats to a single gamma-irradiation in the period of intrauterine development].

作者信息

Tashkhodzhaeva T P, Liaginskaia A M, Gegele T V

出版信息

Radiobiologiia. 1989 Sep-Oct;29(5):696-701.

PMID:2587709
Abstract

A single external exposure of pregnant rats to 2 Gy gamma-radiation caused changes in the functional status of the thyroid gland in offsprings at varying times of the postnatal development. The disturbance of the thyroid hormones balance in the blood, destruction of the thyroid gland combined with high functional tension of secretory elements, and activation of the thyrotropic function of hypophysis were revealed at remote times after irradiation.

摘要

怀孕大鼠单次全身暴露于2 Gy的γ辐射下,会导致后代在出生后不同发育阶段甲状腺功能状态发生变化。在辐射后的远期,可发现血液中甲状腺激素平衡紊乱、甲状腺破坏并伴有分泌元件的高功能张力,以及垂体促甲状腺功能激活。

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