Coculescu M, Dumitrescu C
Endocrinologie. 1984 Apr-Jun;22(2):135-9.
The etiology of cranial diabetes insipidus (CDI) in adult patients has been studied in 164 cases hospitalized in the "G. I. Parhon" Institute of Endocrinology, over the last 10 years. Of those, 109 cases (66,9%) had the idiopathic form whereas 55 had secondary CDI. In the latter group, the most frequently encountered etiologies were traumatic (surgical and accidental head trauma) and tumoral (the primary hypothalamo-pituitary tumors and the metastatic ones had the same incidence). Sex distribution shows males and females to be equally affected. Fifteen cases (9,2%) showed associated allergic syndromes due to the wide use of posterior pituitary powder in Romania. The association of pregnancy with CDI was observed in 13 patients, and a normal evolution of gestation and delivery in 9 patients under therapy with desmopressin (DDAVP). The authors suggest that, at present, there is an increasing incidence both of posttraumatic CDI in adults and of well borne pregnancies.
在过去10年里，“G.I.帕尔洪”内分泌研究所对164例成年住院患者的颅咽管型尿崩症（CDI）病因进行了研究。其中，109例（66.9%）为特发性形式，55例为继发性CDI。在后一组中，最常见的病因是创伤性（手术和意外头部创伤）和肿瘤性（原发性下丘脑 - 垂体肿瘤和转移性肿瘤发病率相同）。性别分布显示男性和女性受影响程度相同。15例（9.2%）因罗马尼亚广泛使用垂体后叶粉而出现相关过敏综合征。在13例患者中观察到妊娠与CDI相关，9例接受去氨加压素（DDAVP）治疗的患者妊娠和分娩过程正常。作者认为，目前成人创伤后CDI和妊娠顺利的发生率都在上升。
