Felding C, Christensen R F, Lindahl F
Scand J Gastroenterol. 1984 May;19(3):365-8.
Eighteen patients with ascites, 9 with cirrhosis of the liver and 9 with malignant disease, were subjected to the ammonia tolerance test by instillation of ammonia transrectally . Arterial blood samples were taken before and 15 and 30 min after the instillation to determine the plasma ammonia concentrations. The results show a significant difference in the plasma ammonia concentration between the two groups of patients after instillation of ammonia. Since the method is non-invasive, it is recommended as a screening test in the differentiation between ascites of cirrhotic and malignant genesis.
18例腹水患者,其中9例为肝硬化,9例为恶性疾病,经直肠滴注氨进行氨耐受试验。在滴注前、滴注后15分钟和30分钟采集动脉血样本,以测定血浆氨浓度。结果显示,两组患者在滴注氨后血浆氨浓度存在显著差异。由于该方法是非侵入性的,因此推荐作为鉴别肝硬化性和恶性腹水的筛查试验。