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50例高压电损伤患者的初期治疗。I. 液体复苏。

Primary treatment of 50 patients with high-tension electrical injuries. I. Fluid resuscitation.

作者信息

Arturson G, Hedlund A

出版信息

Scand J Plast Reconstr Surg. 1984;18(1):111-8. doi: 10.3109/02844318409057412.

DOI:10.3109/02844318409057412
PMID:6740254
Abstract

Fifty patients with high-tension electrical injuries referred for primary treatment to the Burn Center at the University of Uppsala, Sweden during the period 1969 to 1982, have been investigated with special regard to the resuscitation and early complications from internal organs. Seven patients (14%) died, five of them prior to 1974, one in cardiac infarction and four in renal failure. Two died after 1974, one in cardiac infarction and the other in severe shock (98% burn). In 1974 an acute intensive prevention of renal failure was instituted based on forced fluid resuscitation, vasodilators, and supply of alkaline solutions in order to avoid myoglobin and hemoglobin casts in the kidneys. Some degree of renal dysfunction (diminished GFR, a lowered concentration capacity, and an increased fractionate excretion of sodium) was often seen but could usually be reversed without problems. Three patients who developed anuria were successfully treated with hemodialysis. During the years 1974-1982, when the "prevention scheme of renal failure" was applied, all patients with high-tension electrical injury combined with severe myoglobinuria (13 patients) have been successfully treated. 60% of the patients had normal ECG. Five of the seven fatal cases had ST-T abnormalities and two of these patients showed cardiac infarction at autopsy. Early angiography was performed in 20 patients (40%). Obliterated arteries were diagnosed on different levels in 18 extremities in ten patients. The arteriography very precisely indicated the level of amputation of the seriously injured extremities.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1969年至1982年期间,50例因高压电损伤而转诊至瑞典乌普萨拉大学烧伤中心接受初次治疗的患者,针对复苏及内脏早期并发症进行了专门研究。7例患者(14%)死亡,其中5例于1974年前死亡,1例死于心肌梗死,4例死于肾衰竭。2例于1974年后死亡,1例死于心肌梗死,另1例死于严重休克(98%烧伤)。1974年开始实施急性肾衰竭强化预防措施,包括强制液体复苏、血管扩张剂及碱性溶液补给,以避免肾脏出现肌红蛋白和血红蛋白管型。常可见某种程度的肾功能障碍(肾小球滤过率降低、浓缩能力下降及钠排泄分数增加),但通常可顺利逆转。3例出现无尿的患者经血液透析成功治疗。在应用“肾衰竭预防方案”的1974年至1982年期间,所有合并严重肌红蛋白尿的高压电损伤患者(13例)均成功治愈。60%的患者心电图正常。7例死亡病例中有5例存在ST-T异常,其中2例患者尸检显示心肌梗死。20例患者(40%)早期进行了血管造影。10例患者的18条肢体在不同水平诊断出动脉闭塞。血管造影非常精确地显示了严重受伤肢体的截肢水平。(摘要截选至250词)

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Fluid resuscitation of pediatric burn victims: a critical appraisal.小儿烧伤患者的液体复苏:一项批判性评估。
Pediatr Nephrol. 1994 Jun;8(3):357-66. doi: 10.1007/BF00866366.