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家庭中的氡气——肺癌的一个可能病因。

Radon in homes--a possible cause of lung cancer.

作者信息

Edling C, Kling H, Axelson O

出版信息

Scand J Work Environ Health. 1984 Feb;10(1):25-34. doi: 10.5271/sjweh.2366.

Abstract

An earlier case-referent study [Scand j work environ & health 5 (1979) 10-15] has indicated a possible relationship between lung cancer and exposure to radon and radon daughters in dwellings. Indoor radon concentrations seem to depend on both building material and leakage of radon from the ground. This new study, in a rural area, is a further attempt to elucidate the etiology of lung cancer, taking into consideration type of house and ground conditions, as well as smoking habits. Although the choice of a rural study population helped to eliminate various confounding exposures in the urban environment, it limited the size of the study because of the rareness of lung cancer in rural populations. Long-term residents, 30 years or more in the same houses, were studied, and again an association was found between lung cancer and estimated exposure to radon and radon daughters in homes. The data also seem to indicate the possibility of a multiplicative effect between smoking and exposure to radon and radon daughters in homes, but there was also some confounding between these factors in the data.

摘要

一项早期的病例对照研究[《斯堪的纳维亚工作环境与健康杂志》5 (1979) 10 - 15]表明,肺癌与住宅中氡及其子体的暴露之间可能存在关联。室内氡浓度似乎既取决于建筑材料,也取决于氡从地面的泄漏情况。这项在农村地区开展的新研究,在考虑房屋类型、地面条件以及吸烟习惯的情况下,进一步尝试阐明肺癌的病因。尽管选择农村研究人群有助于消除城市环境中各种混杂暴露因素,但由于农村人口中肺癌病例较少,这限制了研究规模。研究对象为在同一房屋居住30年或更长时间的长期居民,研究再次发现肺癌与家中估计的氡及其子体暴露之间存在关联。数据似乎还表明,吸烟与家中氡及其子体暴露之间可能存在相乘效应,但数据中这些因素之间也存在一些混杂情况。

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