IgG-coated latex particles and the identification of sperm antibodies.

The identification of sperm surface antibodies forms an integral part of the investigation of male infertility. We tested 39 randomly selected men for the presence of sperm surface antibodies by using IgG-coated latex particles during mixed antiglobulin reaction (MAR) testing. The latex MAR test results were compared with the red blood cell MAR and the Friberg sperm agglutination test results. The latex MAR is a sensitive indicator and can be employed by physicians to identify the presence of sperm antibodies on the sperm surfaces.