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[抗精子抗体在男性不育中的作用]

[Effect of antisperm antibodies in male infertility].

作者信息

Köksal I, Ozgür G K, Ceylan M, Sivrikaya A, Aker F

机构信息

Tip Fak., Infeksiyon Hast. A. B. D., Trabzon.

出版信息

Mikrobiyol Bul. 1991 Apr;25(2):160-6.

PMID:1745149
Abstract

Antisperm antibodies and their relationship with infertility has been investigated in semen and serum samples of 100 infertile and 25 fertile males. The investigation of antisperm antibodies has been done by latex agglutination test in semen samples and by ELISA procedure in serum samples. In addition, the semen samples have been investigation for several characteristics. Antisperm antibodies have been found 7% positive in blood and 30% positive in semen. In 28.5% of the patients with positive antisperm antibodies in blood, antisperm antibodies in semen have also been found to be positive. For cases with infertility of unknown cause the antisperm antibodies ratio has been found to be significantly high (p less than 0.002). These results have shown the importance of further investigation of antisperm antibodies in cases with infertility of unknown reasons.

摘要

在100名不育男性和25名生育能力正常男性的精液和血清样本中,对抗精子抗体及其与不育的关系进行了研究。通过乳胶凝集试验检测精液样本中的抗精子抗体,通过酶联免疫吸附测定法检测血清样本中的抗精子抗体。此外,还对精液样本的几个特征进行了研究。结果发现,血液中抗精子抗体阳性率为7%,精液中为30%。在血液中抗精子抗体呈阳性的患者中,28.5%的患者精液中的抗精子抗体也呈阳性。对于不明原因不育的病例,抗精子抗体比例显著较高(p小于0.002)。这些结果表明,对于不明原因不育的病例,进一步研究抗精子抗体具有重要意义。

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