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[麻疹患者感染过程动态中外周血的细胞遗传学和免疫学变化]

[Cytogenetic and immunological changes in the peripheral blood of measles patients in the dynamics of the infectious process].

作者信息

Frolov A K

出版信息

Tsitologiia. 1984 Apr;26(4):458-63.

PMID:6740765
Abstract

During the acute period of disease (2-5 days after infection) and later (one month after infection) the associative index of acrocentric chromosomes in T-lymphocytes was higher than in norm, whereas two weeks after infection it did not differ from that in norm. A correlation was found between the quantity of lymphocytes, having a certain number of associated acrocentric chromosomes, the quantity of sensibilized chromosomes, and the number of antibodies. Chromosome alterations in the lymphocytes of reconvalescents were recorded more often than at the start of the illness.

摘要

在疾病急性期(感染后2 - 5天)及之后(感染后1个月),T淋巴细胞中近端着丝粒染色体的联合指数高于正常水平,而感染后两周该指数与正常水平无差异。发现具有一定数量联合近端着丝粒染色体的淋巴细胞数量、致敏染色体数量与抗体数量之间存在相关性。恢复期患者淋巴细胞中的染色体改变比疾病初期更常被记录到。

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