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[局部直肠癌的热放疗]

[Thermo-radiotherapy in local rectal cancer].

作者信息

Berdov B A, Menteshashvili G Z

出版信息

Vopr Onkol. 1984;30(6):87-91.

PMID:6741011
Abstract

The results of preoperative radiation therapy with a cumulative focal dose of 40 Gy were compared in 2 groups of patients suffering from local rectal cancer. 74 patients of the first group received radiation therapy without any additive treatment. 36 patients of the second group before several treatments of radiation therapy received local 915 MHz electromagnetic hyperthermia in the range of 42 to 43.5 degrees C for 1 hour. The patients were operated on 4-6 weeks later. In the second group, full regression was observed in 7 cases. Radical surgery was performed in 15 patients (20.3%) of the first group and 17 patients (47.2%) of the second group. The nature and incidence of postoperative complications in both groups didn't differ significantly. In 4 out of 17 surgical patients of the second group, histologic examination of the resected material failed to detect any tumor elements; the remaining cases revealed deep dystrophic changes.

摘要

对两组局部直肠癌患者术前累积局部剂量为40 Gy的放射治疗结果进行了比较。第一组74例患者接受了单纯放射治疗。第二组36例患者在进行多次放射治疗前,先接受了局部915 MHz电磁热疗,温度在42至43.5摄氏度之间,持续1小时。4至6周后对患者进行手术。在第二组中,观察到7例完全消退。第一组15例患者(20.3%)和第二组17例患者(47.2%)进行了根治性手术。两组术后并发症的性质和发生率无显著差异。在第二组的17例手术患者中,有4例切除材料的组织学检查未发现任何肿瘤成分;其余病例显示有深度营养不良性改变。

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