Pastukhov Iu F, Chepkasov I E
Zh Evol Biokhim Fiziol. 1984 May-Jun;20(3):327-30.
Intraabdominal injections of albino mice of extracts from the brain (2mg/g) and epithelial tissue of the small intestine (1.3 mg/g) of hibernating ground squirrels result within 6 hours in the decrease of the duration of the awake state (by 2.1-2.4 times), inhibition of paradoxical sleep, the increase in the duration of the slow wave sleep, and the decrease in the brain temperature (by 4.5-6 degrees). These indices are affected to a significantly lower extent by injections of intestinal extracts from non-hibernating animals. It is suggested that in homoiothermic animals, changes of temperature homeostasis and sleep cycle are controlled by endogeneous substances which are present in the brain and tissues of the internal organs.
给白化小鼠腹腔注射冬眠地松鼠脑提取物（2毫克/克）和小肠上皮组织提取物（1.3毫克/克），6小时内可使清醒状态持续时间缩短（缩短2.1 - 2.4倍），抑制异相睡眠，增加慢波睡眠持续时间，并使脑温降低（降低4.5 - 6摄氏度）。注射非冬眠动物的肠道提取物对这些指标的影响程度要低得多。这表明在恒温动物中，体温稳态和睡眠周期的变化受存在于脑和内脏组织中的内源性物质控制。
