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[用冬眠动物肠道组织内源性物质处理的小白鼠体温调节变化]

[Changes in thermoregulation in the white mouse treated with endogenous substances from the intestinal tissue of hibernating animals].

作者信息

Pastukhov Iu F, Chepkasov I E

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1983 Nov;69(11):1485-90.

PMID:6653831
Abstract

Intraperitoneal administration of extracts of the small intestine epithelium of hibernating ground squirrels (C. Parryi Rich., C. undulatus) to white mice caused a decrease in oxygen consumption by 50-80%, the 5.5-14.0 degrees C drop in body temperature, inhibition of the muscle shivering thermogenesis, a decrease in heart rate, reduction of locomotor activity, development of hypnogenic effect and a closer dependence of body temperature on environmental fluctuations. The effects lasted for 30-40 hrs. Extracts from the small intestine tissue of non-hibernating ground squirrels caused insignificant changes of these parameters.

摘要

给小白鼠腹腔注射冬眠地松鼠(C. Parryi Rich.、C. undulatus)小肠上皮提取物后,耗氧量降低了50 - 80%,体温下降了5.5 - 14.0摄氏度,肌肉颤抖产热受到抑制,心率降低,运动活性减弱,产生催眠作用,且体温对环境波动的依赖性增强。这些作用持续了30 - 40小时。非冬眠地松鼠小肠组织提取物对这些参数的影响不显著。

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[Changes in thermoregulation in the white mouse treated with endogenous substances from the intestinal tissue of hibernating animals].[用冬眠动物肠道组织内源性物质处理的小白鼠体温调节变化]
Fiziol Zh SSSR Im I M Sechenova. 1983 Nov;69(11):1485-90.
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Hypometabolic and hypothermic factors from small intestine of hibernating ground squirrels (Citellus undulatus).
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