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[胶质瘤的组织结构与计算机断层扫描密度测定结果的相关性]

[Correlation of the histological structure of gliomas with densitometry findings during computer tomography].

作者信息

Melikian A G, Golubev V I, Lobanov S K

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1984 Mar-Apr(2):3-9.

PMID:6741374
Abstract

Local features of the histological structure of malignant glioma tissue are compared with the results of densitometry in computer tomography (CT) with a contrast amplifier. The material for histological examination was collected during stereotaxis biopsy conducted according to CT findings (9 patients) and in examination of the brain of 5 patients who had died without being subjected to operation. The method by means of which anatomical axial sections identical to a series of CT sections were obtained is described. The results in the form of mean values of the coefficients of absorption and the homogeneity of their distribution are shown in accordance with the density of areas with intact brain in each CT section. These data make it possible to detect details of the CT image which are not accessible to visual analysis in some cases and to appraise more objectively the boundaries and spread of the tumors. Besides, they may be used in choosing the targets for stereotaxis biopsy of brain tumors when it is conducted according to the findings of CT. They also increase the informativeness of biopsy.

摘要

将恶性神经胶质瘤组织的组织结构局部特征与使用造影剂的计算机断层扫描(CT)中的密度测定结果进行比较。组织学检查的材料是在根据CT结果进行的立体定向活检期间收集的(9例患者),以及在对5例未经手术死亡患者的脑部检查中收集的。描述了获得与一系列CT切片相同的解剖轴向切片的方法。根据每个CT切片中完整脑组织区域的密度,以吸收系数的平均值及其分布均匀性的形式呈现结果。这些数据使得在某些情况下能够检测到视觉分析无法获得的CT图像细节,并更客观地评估肿瘤的边界和扩散情况。此外,当根据CT结果进行脑肿瘤立体定向活检时,它们可用于选择活检靶点。它们还提高了活检的信息量。

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