Mølster A O, Gjerdet N R
Acta Orthop Scand. 1984 Jun;55(3):342-6. doi: 10.3109/17453678408992370.
The effect of bending and rotational instability on the healing of a femoral osteotomy was studied in rats using intramedullary fixation with nails made of either steel or flexible polyacetal. All osteotomies were made rotationally unstable by reaming the medullary cavity to a diameter wider than the nails. At 16 weeks, four osteotomies had healed, and 17 had not healed. However, bending tests gave higher values for strength and energy absorption in non-unions with flexible as compared to Stiff nails. Rotational instability thus caused a high rate of non-union in the present model, which has given safe healing when the osteotomy has been stabilized for rotation. Flexible nailing increased strength and energy absorption in bones with non-union, but did not affect the incidence of healing.
使用由钢或柔性聚缩醛制成的髓内钉对大鼠进行股骨截骨术，研究弯曲和旋转不稳定性对其愈合的影响。通过将髓腔扩孔至比髓内钉直径更宽，使所有截骨术在旋转上不稳定。在16周时，有4处截骨术已愈合，17处未愈合。然而，弯曲试验显示，与刚性髓内钉相比，柔性髓内钉固定的骨不连在强度和能量吸收方面具有更高的值。因此，在本模型中，旋转不稳定性导致了较高的骨不连发生率，而当截骨术在旋转方面得到稳定时则实现了安全愈合。柔性髓内钉固定增加了骨不连骨骼的强度和能量吸收，但不影响愈合发生率。
