Butte N F, Goldblum R M, Fehl L M, Loftin K, Smith E O, Garza C, Goldman A S
Acta Paediatr Scand. 1984 May;73(3):296-301. doi: 10.1111/j.1651-2227.1994.tb17738.x.
The amounts of lactoferrin, lysozyme, SIgA and SIgA antibodies to E. coli somatic antigens in human milk ingested per day and per kg per day by breast-fed infants were determined during the first four months of life. A gradual decline in the amounts of lactoferrin, SIgA, and SIgA antibodies ingested per day or per kg per day was found, whereas the quantities of lysozyme ingested by the infants rose during that period. These data suggest that the production and secretion of these immunologic factors by the mammary gland may be linked to the ontogeny of the production or catabolism of those components at mucosal tissues of the recipient infant.
在出生后的前四个月，测定了母乳喂养婴儿每天及每千克体重每天摄入的母乳中乳铁蛋白、溶菌酶、分泌型免疫球蛋白A（SIgA）以及针对大肠杆菌菌体抗原的SIgA抗体的含量。结果发现，每天或每千克体重每天摄入的乳铁蛋白、SIgA以及SIgA抗体的量逐渐下降，而在此期间婴儿摄入的溶菌酶量却有所上升。这些数据表明，乳腺对这些免疫因子的产生和分泌可能与受体婴儿黏膜组织中这些成分的产生或分解代谢的个体发育有关。
