Tanaka T, Hsueh C L, Hayashi K, Awai M, Nishihara K, Konaga E, Ichikawa J, Orita K
Acta Pathol Jpn. 1984 Mar;34(2):361-73. doi: 10.1111/j.1440-1827.1984.tb07564.x.
We report a case of a 71-year-old female with primary malignant lymphoma of the breast. The patient noticed a lump in the right breast approximately six years prior to consultation to the Surgical Department because of a rapid growth of the lump, and had no other tumors noticed throughout the body during that period. Histology proved the case to be a "reticulum cell sarcoma" (large cell type) producing IgM in the tumor cells, instead of a breast carcinoma as clinically diagnosed. At the same time, a total of 73 cases of mammary malignant lymphoma among Japanese subjects were reviewed. The criteria for primary or secondary malignant lymphoma of the breast, and histological diagnosis and pathogenesis of the primary breast malignant lymphoma were discussed.
我们报告一例71岁女性原发性乳腺恶性淋巴瘤。患者在因肿块迅速生长到外科就诊前约六年发现右乳有一肿块,在此期间全身未发现其他肿瘤。组织学检查证明该病例为肿瘤细胞产生IgM的“网状细胞肉瘤”(大细胞型),而非临床诊断的乳腺癌。同时,对73例日本患者的乳腺恶性淋巴瘤病例进行了回顾。讨论了乳腺原发性或继发性恶性淋巴瘤的标准,以及原发性乳腺恶性淋巴瘤的组织学诊断和发病机制。