Shiiki S, Fuchimoto S, Inoue F, Kamikawa Y, Gouchi A, Hamada F, Taguchi K, Tanaka S, Orita K
First Department of Surgery, Okayama University Medical School, Japan.
Jpn J Surg. 1991 Mar;21(2):244-8. doi: 10.1007/BF02470917.
A case of primary malignant lymphoma of the breast in a 52 year old woman is described herein. She presented with a painless tumor of the right breast, which was elastic-hard and measured 2 X 1 cm, although there was no lymphadenopathy noted in the axilla or any other regions. Both the biopsy carried out prior to surgery and frozen sections revealed evidence of malignancy, however, histologically, it was difficult to differentiate between malignant lymphoma and carcinoma until staining with the monoclonal antibody MB1 was performed. This allowed a diagnosis of B cell malignant lymphoma of the diffuse large-cell type to be made. The patient remains alive and well 24 months after her mastectomy.
本文描述了一名52岁女性原发性乳腺恶性淋巴瘤的病例。她表现为右乳无痛性肿块,质地硬如橡皮,大小为2×1厘米,腋窝及其他部位未触及淋巴结肿大。术前活检及冰冻切片均显示恶性证据,然而,在组织学上,在进行单克隆抗体MB1染色之前,很难区分恶性淋巴瘤和癌。这使得诊断为弥漫大细胞型B细胞恶性淋巴瘤。该患者乳房切除术后24个月仍健在。