Strömgren L S
Acta Psychiatr Scand. 1984 Jun;69(6):484-90. doi: 10.1111/j.1600-0447.1984.tb02523.x.
To investigate whether it is indicated to make a shift to bilateral technique when the first 6-10 unilateral ECT treatments have produced no improvement in patients with endogenous depression, a retrospective study was made concerning 61 patients 34 of whom (group U) continued with unilateral treatment while in 27 (group UB) a shift was made to bilateral technique. No significant differences were found between the groups with regard to final therapeutic result, only a tendency to better effect in the first mentioned group. This tendency can be explained by the somewhat higher age in this group. The duration of seizures, administration of benzodiazepines, as well as treatment with antidepressive drugs, were equal in the groups, which were thus comparable. It is concluded that since bilateral ECT may severely impair memory for weeks or months the patients should not be stressed by a change to this technique.
为了研究对于内源性抑郁症患者，在最初的6 - 10次单侧电休克治疗无效时是否应改为双侧治疗技术，对61例患者进行了一项回顾性研究。其中34例（U组）继续进行单侧治疗，而27例（UB组）改为双侧治疗技术。两组在最终治疗效果方面未发现显著差异，仅在上述第一组中有效果更好的趋势。这种趋势可以用该组患者年龄稍大来解释。两组的癫痫发作持续时间、苯二氮䓬类药物的使用以及抗抑郁药物治疗情况均相同，因此具有可比性。得出的结论是，由于双侧电休克治疗可能会在数周或数月内严重损害记忆力，不应因改为这种治疗技术而给患者带来压力。
