用稳定同位素测定早产儿膳食中锌的生物利用率。

Determination with stable isotopes of the dietary bioavailability of zinc in premature infants.

作者信息

Ehrenkranz R A, Ackerman B A, Nelli C M, Janghorbani M

出版信息

Am J Clin Nutr. 1984 Jul;40(1):72-81. doi: 10.1093/ajcn/40.1.72.

DOI:10.1093/ajcn/40.1.72

Abstract

Dietary zinc bioavailability was evaluated with the extrinsic tag approach of stable isotope enrichment technology in growing premature infants. The fractional absorption of one dose of 70Zn was determined on 16 occasions in 13 premature infants (birth weight 1135 +/- 40 g, gestational age 29.5 +/- 0.4 wk, mean +/- SE) and was found to be 64.9 +/- 2.7%. The fractional absorption of 70Zn ranged between 48 and 79% and did not appear to be influenced by postnatal age, postconceptual age, body weight, or intake of preterm human milk, fortified-preterm human milk, or premature formula. Therefore, if absorption of the 70Zn dose reflects absorption of dietary zinc, about 60% of dietary zinc is bioavailable.

摘要

采用稳定同位素富集技术的外源性标记法，对生长中的早产儿的膳食锌生物利用度进行了评估。在13名早产儿（出生体重1135±40 g，胎龄29.5±0.4周，均值±标准误）中，16次测定了一剂70Zn的吸收分数，结果发现为64.9±2.7%。70Zn的吸收分数在48%至79%之间，似乎不受出生后年龄、孕龄、体重或早产母乳、强化早产母乳或早产儿配方奶摄入量的影响。因此，如果70Zn剂量的吸收反映了膳食锌的吸收，那么约60%的膳食锌是可生物利用的。