Bion J F
Anaesthesia. 1984 Jun;39(6):560-4. doi: 10.1111/j.1365-2044.1984.tb07362.x.
Continuous intravenous infusions of ketamine and pentazocine have been used to provide analgesia in 18 patients with acute war injuries. The drugs were given alternately. Both drugs produced effective pain relief, but the quality of analgesia was superior following pentazocine because of its sedative properties. Arterial blood pressure and respiratory rate were maintained following ketamine but tended to fall after pentazocine. It is suggested that ketamine would be the better agent in patients with hypovolaemia or respiratory depression.
对18例急性战伤患者持续静脉输注氯胺酮和喷他佐辛以提供镇痛。两种药物交替使用。两种药物均产生了有效的疼痛缓解,但由于喷他佐辛的镇静特性,其镇痛质量更佳。氯胺酮输注后动脉血压和呼吸频率维持稳定,但喷他佐辛输注后则有下降趋势。建议氯胺酮对于低血容量或呼吸抑制患者是更好的药物。