Phillips D C, Ellis F R, Exley K A, Ness M A
Anaesthesia. 1984 Jun;39(6):568-73. doi: 10.1111/j.1365-2044.1984.tb07364.x.
A patient with dystrophia myotonica was given dantrolene sodium to try to provide muscle relaxation during a cholecystectomy. Dantrolene was used as it is accepted that the drug has a place in the control of spasticity and also causes muscle relaxation, whereas conventional muscle relaxants are unable to control myotonia of muscle origin. Dantrolene alone did not provide good enough intubating and operating conditions in this subject. Later studies showed that, after dantrolene, EMG recordings from the patient were not significantly altered, although an impression of a slight increase in the myotonic potentials was gained.
一名强直性肌营养不良患者在胆囊切除术中使用了丹曲林钠以试图实现肌肉松弛。使用丹曲林是因为人们认为该药物在控制痉挛方面有一定作用且能引起肌肉松弛，而传统的肌肉松弛剂无法控制源于肌肉的肌强直。单独使用丹曲林在该患者中未能提供足够好的插管和手术条件。后来的研究表明，使用丹曲林后，患者的肌电图记录没有明显改变，尽管感觉肌强直电位略有增加。
