Schwartz A L, Perman K I, Whitten M
Ann Ophthalmol. 1984 Jun;16(6):560-2, 566.
Twenty-two phakic eyes with progressive low-tension glaucoma had a 360-degree argon laser trabeculoplasty (ALT). Seven of these eyes had diurnal curves performed pre- and two months postlaser treatment to measure the effect of ALT on diurnal pressure variation. Sixteen of the 22 eyes (73%) were clinical successes with a 4.9 mm Hg decrease at 12 months in the successful group. However there was a decreasing pressure lowering effect with time with a mean follow-up of 21.6 months. The diurnal curve data showed a 6.2 mm Hg decrease between the mean pressure pretreatment and two months postlaser treatment. The mean peak pressure posttreatment was 13.29 mm Hg, a 6.17 mm Hg decrease from the prelaser mean peak pressure. The finding of 24-hour pressure control and a reduction in the mean peak pressure confirms the usefulness of ALT in progressive low-tension glaucoma and we recommend that it be utilized as the step in between maximally tolerated medical therapy and filtering surgery.
22只患有进行性低眼压性青光眼的有晶状体眼接受了360度氩激光小梁成形术(ALT)。其中7只眼在激光治疗前及治疗后两个月进行了昼夜眼压曲线测量,以评估ALT对昼夜眼压波动的影响。22只眼中有16只(73%)临床治疗成功,成功组在12个月时眼压降低了4.9毫米汞柱。然而,随着时间推移,眼压降低效果逐渐减弱,平均随访时间为21.6个月。昼夜眼压曲线数据显示,治疗前平均眼压与激光治疗后两个月之间眼压降低了6.2毫米汞柱。治疗后平均峰值眼压为13.29毫米汞柱,比激光治疗前平均峰值眼压降低了6.17毫米汞柱。24小时眼压得到控制以及平均峰值眼压降低这一结果证实了ALT在进行性低眼压性青光眼中的有效性,我们建议将其作为最大耐受药物治疗和滤过性手术之间的一个治疗步骤。