Hyvärinen S
Ann Clin Res. 1984;16 Suppl 41:1-45.
The purpose of this work was to study what kind of types of arteriographic changes occur in patients with claudication, whether the patients can be divided into different groups on the basis of the morphology of the arteriographic findings, whether there are any correlations between the arteriographic findings and the patient's age, sex, occupation, bodyweight, smoking habits, diabetes, hypertonia and the arteriosclerosis of the cerebral and coronary arteries. The series consisted of 490 patients subjected to arteriography of the lower extremities because of claudication. There were 399 males and 91 females. The following changes were seen in the arteries of claudication patients: --tortuosity of the distal aorta and the iliac arteries --arteriosclerotic wall changes varying from intimal thickenings to complete occlusions --collaterals --calcific deposits on vascular walls --aneurysms of the distal aorta. The vessels located proximally to the inguinal ligament were tortuous in 63,1% of the patients and extremely tortuous in 11,2%. Single wall changes were seen rarely; 69% of the patients had more than 6 separate plaques. Smooth and flat plaques were also few. 78% of the patients had wall changes of mixed shapes, and 81% had wall changes with irregular contour. A complete occlusion of a vessel was detected in 67%. Symmetric ASO changes were seen in the extremities of 5,3% of the patients. On the basis of the location and extent of the arteriographically diagnosed wall changes, the series was divided into three main groups. The first main group was further divided into three subgroups and the latter two into two subgroups each. Slightly more than half of the patients belonged to the largest group I A, where arteriosclerotic changes were detected in all segments. Gangrenous changes were most frequent in this group. The patients in group III A, which consisted of diffuse changes of the femoro-popliteal region, had the highest (31,8%) frequency of concomitant diabetes and the second highest (30,3%) frequency of concomitant hypertonia. Hypertension was most frequent as a concomitant disease (42,9%) in group I B, which consisted of the patients with aneurysms of the distal aorta. Single arteriosclerotic changes in the femoropopliteal region were few (1,2%). Vascular tortuosity increased with age. The older age groups had more arteriosclerotic changes particularly in the distal aorta, the deep femoral artery, the superficial femoral artery and the popliteal artery.(ABSTRACT TRUNCATED AT 400 WORDS)
这项研究的目的是探讨间歇性跛行患者会出现何种动脉造影改变；能否根据动脉造影结果的形态将患者分为不同组；动脉造影结果与患者的年龄、性别、职业、体重、吸烟习惯、糖尿病、高血压以及脑动脉和冠状动脉硬化之间是否存在关联。该系列研究包括490例因间歇性跛行接受下肢动脉造影的患者，其中男性399例，女性91例。在间歇性跛行患者的动脉中观察到以下改变：——腹主动脉远端和髂动脉迂曲；——动脉硬化性管壁改变，从内膜增厚到完全闭塞；——侧支循环；——血管壁钙化沉积；——腹主动脉远端动脉瘤。腹股沟韧带近端的血管，63.1%的患者出现迂曲，11.2%的患者极度迂曲。单处管壁改变很少见；69%的患者有6处以上独立斑块。光滑扁平的斑块也很少。78%的患者有混合形状的管壁改变，81%的患者有轮廓不规则的管壁改变。67%的患者检测到血管完全闭塞。5.3%的患者双下肢出现对称性动脉硬化闭塞症改变。根据动脉造影诊断的管壁改变的部位和范围，该系列患者分为三个主要组。第一主要组又进一步分为三个亚组，后两个主要组各分为两个亚组。略超过一半的患者属于最大的IA组，该组所有节段均检测到动脉硬化改变。坏疽性改变在该组最为常见。由股腘区域弥漫性改变组成的IIIA组患者，合并糖尿病的发生率最高（31.8%），合并高血压的发生率次之（30.3%）。高血压作为合并疾病在由腹主动脉远端动脉瘤患者组成的IB组中最为常见（42.9%）。股腘区域单发动脉硬化改变很少（1.2%）。血管迂曲程度随年龄增加而加重。年龄较大的组动脉硬化改变更多，尤其是在腹主动脉远端、股深动脉、股浅动脉和腘动脉。（摘要截选至400字）
