Scintu F
Minerva Med. 1985 Aug 25;76(32-33):1457-61.
To substantiate the hypothesis of a non atherosclerotic origin of abdominal aortic aneurysms, the author compares 40 patients operated on for abdominal aneurysm vs 50 patients operated on for atherosclerotic aorto-iliac occlusive disease at the 1st Surgical Clinic of the University of Cagliari. The mean age of the aneurysm patients was greater than that of the patients with occlusive disease and symptoms of arterial insufficiency of the lower limbs were uncommon. The more statistically significant feature was the difference in the site of lesions: in the aneurysm group, in fact, iliac arteries were uninvolved in 30% of patients, while in the occlusive group lesion involved the iliac tree in all but one case. Furthermore the majority of aneurysm patients showed an undamaged distal vascular bed, in sharp contrast with the occlusive group. Despite of these differences, however, the present series is too small to allow firm conclusions: in consideration of the equality of associate diseases and of lipoprotein patterns between the two groups of patients, abdominal aortic aneurysm and aortoiliac occlusive disease seem to be rather different manifestations of atherosclerosis than really dissimilar diseases.
为了证实腹主动脉瘤非动脉粥样硬化起源的假说，作者对在卡利亚里大学第一外科诊所接受腹主动脉瘤手术的40例患者与接受动脉粥样硬化性主-髂动脉闭塞性疾病手术的50例患者进行了比较。动脉瘤患者的平均年龄大于闭塞性疾病患者，下肢动脉供血不足症状并不常见。更具统计学意义的特征是病变部位的差异：实际上，在动脉瘤组中，30%的患者髂动脉未受累，而在闭塞组中，除1例患者外，所有患者的病变均累及髂动脉。此外，大多数动脉瘤患者的远端血管床未受损，这与闭塞组形成鲜明对比。然而，尽管存在这些差异，但本系列病例数量太少，无法得出确凿结论：考虑到两组患者合并疾病和脂蛋白模式的相似性，腹主动脉瘤和主-髂动脉闭塞性疾病似乎是动脉粥样硬化的不同表现，而非真正不同的疾病。
