De Angelis R C, Giuli G G, Rogano R N, Terra I C
Arq Gastroenterol. 1984 Oct-Dec;20(4):166-9.
Weanling and young adult rats were fed diets containing lactose (L) up to 50 g per 100 g diet for 15 days. The growth rats variation (W), fecal pH, net protein ratio (NPR) and protein efficiency ratio (PER) were determined. In weanling as well as in young adult rats an impairment of L was only detected for higher levels (greater than 20%), and diarrhea occurred only at 50%. The NPR and PER were partially effected by L because of the stimulation of appetite between 1 and 5 g%. The results for 10 and 20 g% of L were not different from controls. It was concluded that rats are not intolerant to levels of L less than or equal to 20%. The evaluation of protein quality in presence of L must be conducted with adapted methodology.
将断奶大鼠和成年大鼠喂养含乳糖（L）的日粮，每100克日粮中乳糖含量高达50克，持续15天。测定生长大鼠的体重变化（W）、粪便pH值、净蛋白比（NPR）和蛋白质效率比（PER）。在断奶大鼠和成年大鼠中，仅在较高水平（大于20%）时才检测到乳糖损害，腹泻仅在50%时出现。由于1%至5%的乳糖刺激食欲，NPR和PER部分受乳糖影响。10%和20%乳糖组的结果与对照组无差异。得出的结论是，大鼠对小于或等于20%的乳糖水平不存在不耐受。必须采用适当的方法评估乳糖存在时的蛋白质质量。
