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Spatial reorganization of low-molecular-weight proteins during cold cataract opacification.

作者信息

Gulik-Krzywicki T, Tardieu A, Delaye M

出版信息

Biochim Biophys Acta. 1984 Jul 16;800(1):28-32. doi: 10.1016/0304-4165(84)90090-4.

DOI:10.1016/0304-4165(84)90090-4
PMID:6743682
Abstract

Freeze-fracture electron microscopy of calf lens nuclear cytoplasm undergoing a cold cataract opacification shows the formation of domains within the bulk cytoplasm. The size distribution of these domains (from a few tens of nanometers to a few micrometers) is compatible with previous size evaluations obtained from light scattering experiments for the 'large scattering elements' responsible for cold cataract opacification. In addition, these domains appear to be devoid of crystallins of higher molecular weight and enriched in low-molecular-weight species.

摘要

相似文献

1
Spatial reorganization of low-molecular-weight proteins during cold cataract opacification.
Biochim Biophys Acta. 1984 Jul 16;800(1):28-32. doi: 10.1016/0304-4165(84)90090-4.
2
Effect of calcium on the calf lens cytoplasm.钙对小牛晶状体细胞质的影响。
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Visualization of crystallin droplets associated with cold cataract formation in young intact rat lens.在年轻完整大鼠晶状体中与冷性白内障形成相关的晶状体蛋白液滴的可视化。
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Membrane alterations during cataract development in the Nakano mouse lens.中野小鼠晶状体白内障形成过程中的膜改变。
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Some aspects of cataract morphology: a SEM-study.
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[Histological studies of congenital cataract. Retardation of denucleation process].[先天性白内障的组织学研究。去核过程的延迟]
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引用本文的文献

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2
CP49 and filensin intermediate filaments are essential for formation of cold cataract.CP49和丝状晶体蛋白中间丝对于冷冻性白内障的形成至关重要。
Mol Vis. 2020 Aug 23;26:603-612. eCollection 2020.
3
Identification of a 70,000-D protein in lens membrane junctional domains.
晶状体膜连接结构域中一种70,000道尔顿蛋白质的鉴定。
J Cell Biol. 1985 Jul;101(1):28-35. doi: 10.1083/jcb.101.1.28.
4
Opacification of gamma-crystallin solutions from calf lens in relation to cold cataract formation.小牛晶状体γ-晶状体蛋白溶液的浑浊化与冷冻性白内障形成的关系
Proc Natl Acad Sci U S A. 1985 Mar;82(6):1701-5. doi: 10.1073/pnas.82.6.1701.
5
Neutron scattering by calf lens cytoplasm. A comparison between two models of cataract.
Eur Biophys J. 1987;14(7):441-7. doi: 10.1007/BF00254868.
6
Visualization of crystallin droplets associated with cold cataract formation in young intact rat lens.在年轻完整大鼠晶状体中与冷性白内障形成相关的晶状体蛋白液滴的可视化。
Proc Natl Acad Sci U S A. 1989 Dec;86(24):9926-30. doi: 10.1073/pnas.86.24.9926.
7
Protein interactions in the calf eye lens: interactions between beta-crystallins are repulsive whereas in gamma-crystallins they are attractive.小牛眼晶状体中的蛋白质相互作用:β-晶状体蛋白之间的相互作用是排斥性的,而在γ-晶状体蛋白中它们是吸引性的。
Eur Biophys J. 1992;21(1):1-12. doi: 10.1007/BF00195438.