源自卵巢乳头状浆液性囊腺癌的细胞系的细胞遗传学
Cytogenetics of a cell line derived from an ovarian papillary serous cystadenocarcinoma.
作者信息
Hill S M, Rodgers C S, Hultén M A, Wilson A P
出版信息
Cancer Genet Cytogenet. 1984 Aug;12(4):321-7. doi: 10.1016/0165-4608(84)90065-7.
The cell line OAW 42 was established from the ascites of a patient with papillary serous cystadenocarcinoma of the ovary. Cytogenetic analysis at three different passages showed that the line was hypotetraploid, with no distinct mode, and was characterized by 14 stable markers, involving chromosomes #1, #3, #4, #5, #12, #17, #18, #20, and #21. Neither component of the translocation t(6;14)(q21;q24), previously reported to characterize ovarian papillary serous cystadenocarcinoma, was found.
细胞系OAW 42是从一名卵巢乳头状浆液性囊腺癌患者的腹水中建立的。在三个不同传代水平进行的细胞遗传学分析表明，该细胞系为亚四倍体，无明显众数，其特征为有14个稳定的标记，涉及1、3、4、5、12、17、18、20和21号染色体。之前报道的可作为卵巢乳头状浆液性囊腺癌特征的t(6;14)(q21;q24)易位的任何组成部分均未发现。
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